DEP Dermoelectroporator - Mattioli Engineering
DEP (DermoElectroPoration) System is the new Non Invasive, Stand alone powered drug-delivery system carrying DermoelectroporationÒ Technology to deliver Ionic drug solution into the body for medical purposes.
As result of more than five years researches, Mattioli Dermoelectroporation®,
technology is consolidated to be an incredible procedure that allows the transdermal delivery of whatever substance operators  want ,  which are otherwise not absorbed into the skin because of the typology and dimension of their own molecules.
Dermoelectroporation® infact, increases the skin's permeability just using some skin's water based channels  opened by a particular controlled current delivered to the patient and allowing the substances to absobed till hypodermis and muscle membranes.
The system has been FDA approved for the "local administration of ionic drug solutions into the body for medical purposes and can be used as an alternative to injections".
DEP System is made of the following devices:
§ Power supply and control base.
§ DEP Transdermal delivery handpiece with
§ Super Precision Liquid Dispenser – Super PLD.
Macromolecules (such as Hyaluronic Acid) previously not transdermally deliverable by traditional Ionthophoresis are now successfully deliverable due to the new DermoelectroporationÒ Technology.
DEP System features:
• Homogeneous drug delivered on the selected area.
• Real time control on the amount of drug to delivered.
• Real time patient's skin impedance measurement for successful drug      delivery.
• Drug administration in a timely manner to avoid waste of product with 100% protection against external agents.
• No Electrolysis effect – No drug PH modification
• No need of Pre-charged compounds/ Carrying Gels/ specific products or particular preparations.